Probiotics have garnered a lot of attention since the 1990s. An industry that initially took off in the form of food sources (i.e., pickles, yogurt, kimchi, and sauerkraut) quickly expanded to house beverages and supplements. Why is there such an exploded awareness of probiotics? These bacteria strains have been shown to enhance the gut microbiome. This ensures healthy bacteria essential for fighting off bad bacteria and harmful invaders and protection against conditions such as diabetes, mental health issues, cancers, and inflammation-related consequences.
Since the last time our editorial team covered probiotics, newer options have surfaced, hence, the reason for this update. This guide introduces 33 top probiotics trusted to positively influence gut and heart functions, digestive and immune systems, skin, mental and physical health, and weight management. Throughout this piece, individuals will be able to familiarize themselves with the impact of probiotics on the entire body while taking this opportunity to study different approaches for wellness. Without any further delay, here are our top contenders:The Top 33 Best Probiotic Supplements in 2022ActivatedYou Advanced Restorative ProbioticAdvanced Bionutritionals Advanced Probiotic FormulaBioFitBiOptimizers P3-OMBioTRUST Pro-X10Earth Echo ProbioticEarth Echo Vitality Bliss BitesRevival Point FloraSpringGundry MD 24 Strain ProbioticJust Thrive Probiotic & AntioxidantLeanBiomeLive Conscious Pro-45Microbiome Plus+ Colon Cleanse & DetoxNucific Bio X4Nuzena Probiotic 40 Gut Boost +Organifi BALANCEOrganixx ProBiotixx+OrthobiomeOweli ProbioticPhytAge Labs Replenish 911Golden After 50 Probio-LiteProbiotic America Perfect BioticsZenith Labs Probiotic T-50Probulin Total Care ProbioticsPurality Health Micelle Liposomal ProbioticUnify Health Labs Multi-GI 5UpWellness Probiotic +Vital Plan Advanced BioticVital Plan Biome BoostVitaPost Probiotic 40-BillionSeed DS-01Simple Promise Ovuna1MD Nutrition Complete Probiotics PlatinumAdvanced Restorative Probiotic
As the name suggests, Advanced Restorative Probiotic is a probiotic formula intended to prime the digestive system with healthy bacteria. In so doing, individuals can expect peak performance and total-body wellness. ActivatedYou explained that their formula helps colonize the system, may set one up for improved mood and energy levels, and ultimately ensures homeostasis for a healthy immune function, radiant skin, and gut health.
At ActivatedYou, helping someone implies understanding and treating them as a whole person – mind, body, and spirit. Through their products and education, the team strives to “approach problems right from the source, to help you live your healthiest, happiest life.” Speaking of products, their formulations entail cutting-edge health and nutrition with age-old Eastern traditions and ingredients. In fact, a health advocate and gut expert have been consulted in creating each formula!
One serving (1 capsule) contains a 30 billion CFU-proprietary probiotic blend of 30 strains. Some examples include L. acidophilus, Propionibacterium freudenreichii. Shermanii, L. brevis, L. bulgaricus, L. casei, L. paracasei, L. plantarum, L. rhamnosus, B. adolescentis and L. reuteri. For a complete list, visit their official website!Advanced Probiotic Formula
In contrast to the first introduced supplement, we have the Advanced Probiotic Formula by Advanced Bionutritionals. This dietary supplement is intended to deliver the body with foundational probiotic bacteria and essential prebiotics for digestive support, cognitive function, memory, thinking, and whole-body health.
At Advanced Bionutritionals, the team works closely with their suppliers and manufacturers to ensure each supplement is fresh and reflects quality ingredients. A comforting fact about them is that the team entails nothing but medical experts such as Dr. Frank Shallenberger, MD, Dr. Janet Zand, O.M.D., L.Ac, Steve Kroening, ND, and Dr. Isaac Eliaz, MD, MS, L.Ac.
Another desirable facet is their use of patented ingredients, preferred for their testing and research efforts. Regarding the formula, each serving (1 capsule) comprises 15 billion CFU in the form of L. acidophilus DDS, B. lactis UAB1a-12, B. longum UABI-14, and B. bifidum UABb-10.BioFit
Company: S.O LabsStarting Price: $59
BioFit is an all-natural dietary supplement formulated to induce weight loss by balancing the gut. The latter is allegedly imperative to ensure healthy digestion and metabolic function, both of which have a role to play in weight management. A slowed metabolism forces the body to pack unwanted fat, creating unnecessary setbacks in goals. By introducing good bacteria, metabolic rates can be heightened, allowing one to notice changes to their physique. Obviously, probiotics alone do not suffice for significant change, hence, the need for a healthy exercise routine and proper meal planning.
At the time of writing, very little has been disclosed about S.O Labs. However, we know that each serving (1 capsule) contains 5.75 billion CFUs of Bacillus Subtilis, L. rhamnosus, L. casei, L. Plantarum, L. acidophilus, B. longum, and B. breve. Is this information enough to invest in? We’ll let you be the judge of that!P3-OM
BiOptimizers claim to have formulated P3-OM using a new patented “SUPER-strain” for optimal protein digestion and assimilation. Prepared as a freeze-dried culture, this supplement ensures the included probiotics remain potent in the digestive system. Specifically, each serving (1 capsule) contains 10 billion CFU of a proteolytic probiotic called L. Plantarum OM.
This team was interested in creating P3-OM due to the negative impact of an imbalanced immune system, i.e., snowballing into allergies, autoimmune diseases, inflammation, and food sensitivities, to list a fraction. Besides balancing the immune system, P3-OM might strengthen the gut barrier, produce antimicrobial substances and enzymes, promote the gut-brain axis, and activate vitamins for complete health.
Concerning BiOptimizers, the brand took shape after the president and co-founder Wade Lightheart lost his 23-year-old sister to cancer. Realizing that health is too precious to take lightly, he eventually helped his best friend and co-founder, Matt Gallant, lose weight. The transformation was all it took to confirm the ongoing need for fitness programs, digestive enzymes, and organic plant-based protein. Their policy is, “If we can’t build the best product in that category, forget about it.”Pro-X10
Pro-X10 is an advanced probiotic and gut health formula. How is this any different from a conventional supplement? According to BioTRUST, their solution provides live probiotics that have been protected using microencapsulation technology. The latter is an acid-resistant coating proven to increase the viability and activity of probiotics. Together, these facets support a healthy gut, digestive tract, and immune system. Possible indirect outcomes include a healthy mood, alleviation of stress, and recovery after exercise.
Born in 2011, co-founders Josh Bezoni and Joel Marion decided to launch a mission-based protein and collagen company that was the most authentic, honest, and charitable, all while putting customers first. Within one year of embarking on this journey, the duo sold over 1 million products. Starting with their solutions, they supposedly only use ingredients rooted in nature and those backed by certificates of analysis (CoAs), restrict any flow of artificial ingredients and have their products tested by third-party labs.
That’s not all; they’ve kept their end of the bargain in terms of charitable donations by providing 5.3 million nutritious meals through No Kid Hungry, giving $2 million and granting 215 life-changing wishes via Make-A-Wish, building schools through Pencils of Promise and with Water.org and partnering with many others. Regarding the ingredients, each serving delivers 5 billion CFU of B. breve, B. lactis, L. acidophilus, L. Plantarum, L. rhamnosus, and B. subtilis, and 7.5mg of a prebiotic called PreforPro.Earth Echo Probiotic
Earth Echo Probiotic is yet another solution that aims to strengthen the immune system to provide healthy defense against harmful invaders. This dairy-gluten- and soy-free, organic, and vegan supplement has the potential to smooth out digestion issues, reduce occasional uncomfortable gas, help absorb nutrients, balance hunger hormones, tame cravings, and improve metabolism. Ingredients responsible for these benefits include 50 billion CFU of L. acidophilus, B. lactis, L. Plantarum, L. paracasei, L. casei, L. Brevis, L. rhamnosus, B. breve, B. bifidum, B. longum, L. gasseri, and L. salivarius.
As for Earth Echo, the team believes that when we feel good, we do good. They claim to sustainably source only the best organic, non-GMO ingredients with this philosophy in mind. In addition to tapping into Mother Nature’s nutrient-dense superfoods, Earth Echo promises to respect science, ultimately finding a balance between the two. At the end of the day, what does it mean to support Earth Echo? Here’s what the team sees:
“Every time you choose an Earth Echo product, you’re taking a stand to better the world we live in. You’re showing that you’re serious about feeling your best so you can make a bigger impact. You are supporting a movement.”Vitality Bliss Bites
Vitality Bliss Bites are postbiotic dark chocolate bites aimed at curbing cravings, providing consumers with a guilt-free treat, and optimizing gut health. These bites are the first of their kind, proving that healthy bacteria can be enjoyed. For those unfamiliar with the term, postbiotics are simply “waste” products of probiotics. Undeniably, waste has a negative tone to it, but in this case, it is beneficial for the immune system to certain allergies and may lessen the effects of digestive disorders. Each serving (i.e., a 10g square) is made by bringing together the likes of Organic Cacao Beans, Organic Coconut Sugar, Organic Agave Inulin Powder, Spore-based B. coagulans GBI-30 6086, and Organic Sunflower Lecithin.FloraSpring
FloraSpring is a dietary supplement formulated to boost the digestive system, support a healthy and active metabolism, reduce inflammation and cravings, and increase energy, mood, and focus. Developed by Dr. Steven Masley, MD, FAHA, FACN, CNS, CCD, each serving delivers 25 billion CFU of L. acidophilus, L. fermentum, L. gasseri, L. rhamnosus, B. breve, along with other booster strains.
At Revival Point, the goal is “to provide men and women [with] a healthy and high functioning digestive system, which is a foundation of good energy, health, and happiness.” Made in the U.S., their products are all-natural, vegetarian, gluten, soy, allergen, and dairy-free and represent the coming together of doctors and researchers. Getting back on the formula topic, Dr. Masley justified the use of five strains as having the ability to help produce a healthy gut. A healthy gut microbiome supposedly dictates how the immune system functions, determining weight loss results and other health issues.
The booster ingredients have been included to possibly tend to other indirect, gut-related concerns such as anxiety, diabetes, poor skin health, and high blood pressure. Considering everything, individuals should be careful in their purchases, as previous customers complained that the company took out money even when a product was not purchased. It is unclear whether they purchased from the original website, but it is a concern to be mindful of.24 Strain Probiotic
24 Strain Probiotic is exactly what it is made to be, a probiotic supplement containing 24 different probiotic strains (each one intended to help balance gut bacteria). This solution is most suitable for those looking to ease gas and bloating, improve digestive regularity, and maintain and nourish a healthy gut. Delivering 30 billion CFU per capsule, individuals can anticipate equipping their bodies with L. acidophilus, B. lactis, B. breve, L. Plantarum, L. rhamnosus, L. casei, and L. salivarius, to list a fraction.
Bearing the latter in mind, Gundry MD was founded by Dr. Steven Gundry, a former cardiac surgeon, medical innovator, and respected author. His goal for this company is “to help dramatically improve human health, happiness, and longevity through [his] unique vision of diet and nutrition.” In fact, it was a patient outcome that changed his view on conventional medicine.
In particular, when he was Head of Cardiothoracic Surgery at Loma Linda University, he was asked to treat a chronically ill, overweight patient. People saw him as a hopeless case where even surgery was ineffective. The same person deemed inoperable managed to reverse his heart-threatening symptoms with something as simple as natural, dietary nutrients. After delving into research, Dr. Gundry discovered that one of the keys to strong, sustainable health is beneficial microbes. He has been studying the human microbiome – for 14 years and counting.Just Thrive Probiotic & Antioxidant
Just Thrive’s Probiotic & Antioxidant is a microbiologist-formulated, potent, and effective spore probiotic supplement with 1000x better survivability. This clinically tested solution has been proven to support immune, digestive, and emotional health, improve flora balance and energy levels, and encourage healthy weight management in just 30 days.
This solution, apart from most, is the inclusion of B. indicus HU36, a patented strain that produces antioxidants in the digestive system. Antioxidants help improve immunity, permitting utmost defense against harmful bacteria. In addition to the aforesaid strain, each serving also delivers B. coagulans (SC-208), B. clausii (SC-109), and B. subtilis HU58, resulting in a solution with 3 billion CFU.
Founders Tina and Billy Anderson once worked in the pharmaceutical industry and were forced to choose between right and profitable. Explicitly, the duo was asked to lower their minimum cholesterol benchmarks to prescribe more medication to more patients. Taken aback, they started putting two and two together. Most people are prescribed more than one medication only to lead to other health consequences.
And so, they left their careers behind to dive deeper into natural and progressive health. This is how they landed on the power of beneficial gut bacteria, namely spore probiotics. According to the duo, “Specialized spore-based strains had the unique ability to survive the journey from mouth to gut and arrive fully alive.” After meeting microbiologist Kiran Krishnan, they formed a partnership that allowed the former parties to get exclusive rights to potent probiotic strains, and that’s how Just Thrive was born.LeanBiome
Company: Lean for GoodStarting Price: $59
LeanBiome is a weight management supplement that diversifies the gut microbiome with “lean bacteria.” These strains are believed to suppress hunger, dampen cravings, fire up the metabolism, and reduce fat storage. The key takeaway is the need for diverse strains for a rich gut. Otherwise, results are not as prominent, explains Lean for Good. We know very little about the Lean for Good team at the time of writing, but at least specifics on the formula have since been disclosed. Each serving (1 delay-release capsule) includes 20 billion CFU of L. gasseri, L. rhamnosus, and a proprietary blend of L. fermentum, L. paracasei, L. Plantarum, B. bifidum, B. lactis, B. longum, and B. breve. Besides probiotics, Inulin (200mg) and Green Tea Phytosome (300mg) have been considered prebiotics and caffeine.Pro-45
Pro-45 is a broad-spectrum probiotic formula that features not one but 45 billion live cultures and 11 clinically studied probiotic strains. Live Conscious main goal for this supplement is to ensure that the body provides acid and bile resistance fundamentals and colonizes the gut. Along with probiotics, this team also included one source of prebiotics to help promote vitality and growth of good gut flora.
At Live Conscious, the mantra and promise are “my mind is sharp, my body healthy, my spirit at ease.” How is the latter maintained? The team pledges to have incorporated traditionally sourced offerings that have been clinically proven to balance the mind, body, and spirit. In addition to choosing quality ingredients, they are confident in their transparency level, whether through labeling or product potency with independent third-party testing.
So, what does each delay-release capsule exemplify? 46.4 billion CFU in the form of L. acidophilus L61A, B. lactis B42L, B. longum B12L, B. bifidum B66B, L. Plantarum L23P, L. bulgaricus L88B, L. casei L30C, L. salivarius L10S, LactoSpore, L. gasseri L22G, L. rhamnosus L08R, and Nutraflora.Colon Cleanse & Detox
Company: Microbiome Plus+Starting Price: $28.49
Developed by doctors, the Colon Cleanse & Detox by Microbiome Plus+ supplement is a supplement trusted to cleanse and detoxify the intestines, support healthy metabolic functions, alleviate gas and constipation, ensure fiber requirements are met, boost metabolism immune function, and deliver an adequate source of prebiotics fundamental for probiotic strength. The decision to take the detoxification route is deemed necessary because by safely eliminating toxins, individuals can anticipate increased nutrients absorption, reversing symptoms linked to an imbalanced gut.
On the subject of the makers, they affirm the Microbiome Plus+ line of products uses the science of microbiome to offer proven ingredients that support digestive functions and overall wellness. In fact, the team wants everyone to focus their attention on the Microbiome Plus+’s L. reuteri NCIMB 30242, described as “one of the few probiotic strains granted GRAS status and has been shown in several human clinical trials to improve cardiovascular and other health markers.”
Finally, we have the ingredients responsible for the aforesaid benefits, which include Fennel Seed Powder (190mg), Cascara Sagrada Bark Powder (175mg), Ginger Root Powder (60mg), Goldenseal Root Powder (50mg), Psyllium Husk Powder (190mg), Buckthorn Bark Powder (60mg), Licorice Root Powder (60mg), Rhubarb Root Powder (50mg), and a 55mg proprietary blend of Citrus Pectin, Flaxseed, Aloe Vera, Cayenne, Senna Leaf, Oat Fiber, and Prune Powder.Bio X4
Bio X4 is a 4-way defensive strategy designed to ward off unhealthy cravings, digestive issues, and poor metabolism. With emphasis placed on healthy weight, the Nucific team wants everyone to experience optimized digestion from the inside and out. What is it about this system that makes it a 4-in-1 solution? As per the claims made, each serving includes digestive enzymes (43mg of Amylase, Bromelain, and Lipase combined), Caralluma Fimbriata (166mg), Green Tea Extract (100mg), and a 4 billion CFU probiotic blend of L. acidophilus, L. rhamnosus, L. Plantarum, B. lactis, and B. animalis.
Concerning Nucific, their tactic entails simple nutrition, or the use of real food, giving credit to the latter as the foundation for all their solutions. Board-certified by the American Board of Internal Medicine, Dr. Amy Lee MD partnered with Nucific “to help you get the body and life [everyone] deserves,” stressing their ongoing efforts in maximizing their solutions’ ability, “to manage weight, improve energy and feel healthier overall.”Probiotic 40 Gut Boost +
Designed by health professionals, Probiotic 40 Gut Boost + is a natural formula poised to give the gut the kickstart to improve the digestive system, nutrients absorption, and good riddance to bad bacteria and inflammation. The ingredients that bring these benefits to life include MAKTrek 3-D (a bi-pass technology and probiotic delivery system) and 40 billion CFU of L. acidophilus La-14, B. lactis BL-04, L. Plantarum Lp-115, L. paracasei Lpc-37, Marine Polysaccharide Complex, and Fructooligosaccharide (FOS) per 2 capsules.
So, why Nuzena? Nuzena is a natural supplement company that uses an integrative approach to improving health and wellness. This goal doesn’t merely stop at delivering products. The team’s integrative approach factors the growing need for “unrivaled quality, transparency, and education surrounding natural health products and services.”
Then there’s the fact that Nuzena combines the experience of registered dietitians, food scientists, and nutritionists willing to offer free consultation and comprehensive health and wellness reports. These reports also include external tools to implement an action plan. How can anyone neglect their commitment to third-party testing? For these reasons, which are just some examples of what individuals should be expecting, we are persuaded by Nuzena.BALANCE
Straying away from capsules, we have Organifi’s BALANCE, a convenient stick filled with five resilient strains to empower the gut. By empowering the gut, the team is confident benefits such as improved digestion, nutrients absorption, and strengthened immune system are likely to follow suit. Organifi believes “the key to health begins in the gut.”
Modern life has been a danger for the most part because it has since introduced our bodies to pesticides, antibiotics, chronic stress, and microplastics that destroy the microbiome. BALANCE contains 20 billion CFU of L. paracasei, S. boulardii, L. acidophilus, L. rhamnosus, and Jerusalem Artichoke to promote healing.
If the former isn’t impressive enough, the story of Organifi is definitely one for the books. On a mission to make a healthy lifestyle attainable by all, the team realized great deficiencies in the market. They were dissatisfied with “quick solutions” and empty health promises that left people frustrated and feeling hopeless.” After grasping the uniqueness and health benefits of superfoods, Organifi took shape. Convenience, quality, potency, and contribution to society are some of the many features that define the brand, which will catch people’s attention.ProBiotixx+
ProBiotixx is a daily use, tested probiotic supplement that restores healthy gut balance. In so doing, one might notice lessened frequency in gas, cramps, and bloating. What captivated us some more were remarks regarding the use of nothing but 2.5 billion CFU of L. Plantarum (1 capsule) by naturopath physician Dr. Melissa Gallagher.
She said, “the true power of ProBiotixx+ is that it can help balance the gut/brain connection. Particularly, research shows certain probiotics like Lactobacillus Plantarum can balance our neurotransmitter health, bringing calm to the brain, easing depression, promoting sleep and an overall sense of peace.” Unmistakably, Organixx relies heavily on a medical expert for the overall formulation, who spent the past 12 years studying within this realm.
As for the company’s mission, CEO Jonathan Hunsaker shared that it is to support everyone to become the healthiest versions of themselves, i.e., “Everything we do – from the pure ingredients to the meticulous production processes, to the fairest pricing – is geared toward you reaching your goals,” he says.Orthobiome
Company: Healthy Living AssociationStarting Price: $29.97
Orthobiome is defined as a complete probiotic supplement encompassing nine different probiotic strains. This grouping has the potential to relieve and support low energy, weight management, brain fog, digestive problems, food allergies, happy moods, and skin-related issues. So, what are the nine strains of utmost importance to The Healthy Living Association? Each serving (1 capsule) has been equipped with 20 billion CFU of L. acidophilus, B. subtilis, L. Helveticus, B. longum, L. gasseri, L. rhamnosus, L. casei, L. Plantarum, and B. breve.
Now getting on the topic of the company, The Healthy Living Association, a trademark of Legendary Ventures, was founded on the belief that Americans can become healthier by choosing natural remedies. Since the status quo doesn’t always work, and the healthcare system is perceived as being broken, the team wants to create researched solutions that can be relied upon. While their devotion is nice to see, it doesn’t truly reflect quality, worth, or efficacy. Will the latter cause problems later? This should be pondered upon before placing an order.Oweli Probiotic
Oweli Probiotic is a full-spectrum probiotic supplement meant to optimize gut health. The team trusts their solution can better digestive health, metabolism, weight management efforts, and immune function by concentrating on holistic strategies. At Oweli, the goal is to induce our natural state of being, which requires making the right choices and having fun. Forget all the nutritional jargon, as this team intends to better health using essential nutrients that assist the body’s interrelated structures instead of providing a temporary band-aid.
An uncanny detail about Oweli’s solution and that of Nuzena is how identical the formulas are. With Oweli, each serving of 2 capsules provides MAKTrek 3-D (a bi-pass technology and probiotic delivery system) and 40 billion CFU of L. acidophilus La-14, B. lactis BL-04, L. Plantarum Lp-115, L. paracasei Lpc-37, Marine Polysaccharide Complex, and Fructooligosaccharide (FOS), all which are also found in Nuzena. Just because Oweli costs less, does it make it superior? Or will Nuzena prevail because of the involvement of health professionals and access to free consultations? We will leave it to the people to decide!Replenish 911
Replenish 911 is a dietary supplement that combines active sources of probiotics to immediately replenish the gut and alleviate upset stomach and poor immune function. The team at PhytAge Labs has designed this solution with weight management-related setbacks in mind. So, by taking Replenish 911 as recommended, individuals might notice an increase in mood and motivation, and most importantly, desired results. Each serving (1 capsule) unites the likes of B. subtilis, L. rhamnosus, L. casei, L. Plantarum, B. longum, B. breve, and L. acidophilus, totaling 5.75 billion CFU.
Since 2015, PhytAge Labs has devoted themselves to partaking in top-notch research and development to guarantee quality supplements. Physicians are supposedly involved, and the team also relies heavily on health data and medical research studies available. This strategy permitted them to launch their first-ever PhytAge PLUS supplement, which remains as a “highly acclaimed phytoceramide-based skincare supplement.” The latter’s success naturally led PhytAge Labs to venture into different health conditions, permitting them to launch over 20 products and counting!Probio-Lite
Company: Golden After 50Starting Price: $69
Probio-Lite is a probiotic formula made to assist healthy digestive performance. The strains found inside this supplement are poised to help balance the gut, soothe the digestive tract, and ensure optimal gut health for complete bodily wellness. According to the claims made, Probio-Lite might make people feel lighter on their feet and rid the esophagus of occasional, minor discomfort when lying down.
Interestingly, they believe this solution will promote the ability to snack late at night and consume heavier meals. We do not encourage this or anything that might put the body in shock. Regarding the ingredients expected to produce such transformative changes, each serving (1 capsule) will be delivering 5 billion CFU of L. acidophilus, L. salivarius, L. Plantarum, B. lactis, B. bifidum, L. fermentum, L. reuteri, and B. longum.
At Golden After 50, only one thought remains strong in their mind, “to help men and women during their golden years continue living life on their own terms and without having to depend on others.” This team commits to launching products created using nothing but natural compounds backed by science each day. Additionally, they’ve partnered with researchers and experts across the globe in search of the latest, rarest, and most exotic compounds that are safe and provide plenty of relief.Perfect Biotics
Perfect Biotics is a digestive and immune support designed to liberate individuals from gas, bloating, and fatigue. Using an 80/20 ratio of good versus bad bacteria, the makers, Probiotic America, avows that the immune system will have full strength. When taken as directed, one can also hope to increase energy and improve metabolism and digestion.
Probiotic America selected strains with the ability to survive the journey through the stomach and eventually land in the digestive tract. Specifically, each capsule contains 30 billion CFU of L. acidophilus, B. lactis, L. Plantarum, L. rhamnosus, L. casei, L. salivarius, L. bulgaricus, B. breve, and L. paracasei, to list a few.
On the topic of the company, Probiotic America was established on the belief that “probiotics may hold the key to the future of nutrition.” The team underscored the human body as the home to 100 trillion bacterial cells, outnumbering “human cells” by 10 to 1. To their knowledge, our bodies have faced the worst with the introduction of antibiotics. Why? The latter reduces the amounts of good bacteria in the gut, negatively influencing the gut microbiome and inducing a series of health flaws.
And so, a board-certified family practitioner of over ten years, Dr. Cary Nelson, joined forces with this company to further his mission of helping people with digestive problems. In all honesty, Perfect Biotics was founded on his research on the latest nutritional breakthroughs!Probiotic T-50
Probiotic T-50 is a probiotic supplement that supports gut microbiome and healthy immune function and combats bloating gas and bowel irregularities. Above all, each serving allegedly equips the body with unique strains for healthy cognitive function and fat loss. Dr. Ryan Shelton, NMD, formulated this solution around key “Director Probiotics,” which produce new bacteria and help regulate the thousands. This is definitely an attention-grabbing tactic, as most supplement providers in this guide focused on introducing new ones, omitting existing ones.
Therefore, each serving (1 capsule) includes 50 billion CFU of L. acidophilus, B. lactis, L. bulgaricus, L. rhamnosus, L. casei, L. Brevis, L. salivarius, L. Plantarum, B. bifidum, B. longum, and S. thermophilus. Before anything else, what is Zenith Labs? Zenith Labs embodies health professionals whose shared goal is to celebrate whole-body solutions that tend to the body’s natural healing processes. All their natural ingredients are selected based on traditional remedies with scientific backing. Dr. Ryan is at the center of all this, whose extensive knowledge of alternative medicine plays a vital role in the supplements offered.Total Care Probiotics
Total Care Probiotics can be perceived as a one-stop-shop for all gut-related support. Inside each serving (delivering broad-spectrum support), individuals will find a unique blend of 15 strains brought together for optimal potency. These include Lactobacillus Blend + Lactobacillus Fermentation Blend (from Organic Beet, Organic Kale, Organic Raspberry, Organic Fig, and Organic Blueberry), L. acidophilus, L. fermentum, L. rhamnosus, L. reuteri, L. Brevis, L. bulgaricus, L. Helveticus, B. longum, B. lactis, B. bifidum, S. boulardii, P. acidilactici, P. pentosaceus, P. freudenreichii, S. thermophilus and a 40mg Postbiotic + Prebiotic Blend (Maktabolite + Inulin). Did you notice that of the 20 billion CFU, 8 billion comes from fermented fruits and vegetables?
A facet worth discussing regarding Probulin as a company is that its complete attention has been directed towards digestive health. Their ability to offer multi-strain total gut health support must incorporate scientifically acclaimed MAKTrek 3-D Delivery System and shelf stability. They’ve also studied the best means of upkeeping survival rates and resistance to different pressures created by environmental exposure. Their products come in insulation packaging to ensure that strains remain alive until they reach the digestive tract. Ultimately, knowledge is power, which gives Probulin a lot to be proud about.Micelle Liposomal Probiotic
Purality Health Micelle Liposomal Probiotic is one where only one particular strain is celebrated in the guide. Why have they taken this route instead of creating synergy between several? According to the team, L. rhamnosus (35 billion CFU) is the most studied and effective strain. It has been linked to enhanced gut health and may support child development, brain health, and weight management.
Lactoferrin, an iron-binding protein extracted from milk, has been considered to further the formula. This addition binds closely to the included nutrient and maximizes survival rates. Then, we have MCT fatty acids, which the team deems is fundamental for healthy energy. RcME Delivery was incorporated as a final touch, taking lactoferrin to the next level.
All things considered, the goal at Purality Health is simple: “To provide high-quality products that enable people to lead healthier lives.” Initially established as a partnership between 3 health enthusiasts, the brand quickly became a favorite because of its use of organic, non-GMO, and gluten-free ingredients supported by research while being completely transparent in their processes. If these features do not suggest anything about this company’s commitment, we don’t know what will!Multi-GI 5
Company: Unify Health LabsStarting Price: $69.95
Multi-GI 5 is a dietary supplement designed to unveil five important benefits: 1) healthy digestion, 2) improved weight management, 3) increased energy, 4) a healthy GI lining, and 5) a balanced gut flora. Together these pieces play a vital role in attaining whole-body health. How has this team mastered the art of holistic solutions? By introducing the body to 3 unique health blends, each filled with prebiotics, probiotics, and GI-boosting ingredients.
For people suffering from digestive discomfort, low energy, gas, bloating, weight gain, or other health issues, the likes of Oligosaccharides (4g), 433mg-GI Health Blend of Fermented L-Glutamine, Zinc-Carnosine Complex, Magnesium BHB, Deglycyrrhizinated Licorice Root Extract, BioPerine, and Berberine Hydrochloride and finally, a 37.64mg blend of L. gasseri, B. coagulans, L. rhamnosus, L. casei, and L. Plantarum should be of utmost importance.
Remember when world-renowned musician, singer, record producer, and A&R executive, among others, Randy Jackson lost 114 pounds and kept it off? He sought help from physicians, nutritionists, fitness experts, personal trainers, chefs, and psychiatrists who covered every angle of weight-related issues. Furthermore, he credits his attitude for his life-transforming endeavor and insists that it is “about more than diet and calories.” Fortunately, he decided to make it his mission to help others struggling with their respective journeys, leading him to a partnership with Unify Health Labs.Probiotic +
Probiotic + brings together six strains, three herbal adaptogenic superfoods, and fiber to help with bowel movements, accelerate fat loss, increase energy, diversify the gut microbiome, and support immune function. Formulated by in-house naturopathic physicians, this solution is deemed a must-have, especially considering the impact that healthy bacteria have on the entirety of our bodies.
Speaking of impact, the only way to reap the supposed benefits is by taking a capsule a day, which includes 5.5 billion CFU of L. acidophilus, L. rhamnosus, L. Plantarum, B. bifidum, B. breve and S. boulardii, VitaFiber (40mg), Holy Basil (200mg), Ginger (200mg), and Turkey Tail Mushroom (100mg). What we appreciate about UpWellness is its detailed approach to labeling. Not a single brand on this list went as far as breaking down the CFU concerning strains. In this case, L. rhamnosus was prioritized!
The company tagline is “Nutrient-Rich Living,” which the team sees as more than just nutrients from food, i.e., physical activity, sleep, laughter, humor, relaxation, fun, and everything that constitutes our very existence. If their definition isn’t captivating enough, individuals will find comfort in the expertise onboard.
First, we have a medical director and formulator, Dr. Josh Levitt, who allegedly “draws upon the science of both conventional and naturopathic medicine and artfully combines the two into a unique “best of both worlds” approach.” Who can forget Dr. Amanda Levitt, another medical director whose clinical experience has been infused in UpWellness solutions!Advanced Biotic
Developed by Bill Rawls, M.D., Advanced Biotic is formulated to support the gut microbiome’s integrity and boost the immune system. These facets alone allegedly suffice to achieve a whole-body balance. As put by the team, recent research has demonstrated that ultra-low concentrations of microbes exist in all tissues, so our health depends on its flourishment.
Hence, the goal for Advanced Biotic is two-fold: 1) to directly induce microbiome wellness and 2) to indirectly protect by warding off invaders. To ensure both indirect and direct benefits, Dr. Bill Rawls chose each serving (3 capsules) to reflect the coming together of Japanese Knotweed Extract (400mg), Cat’s Claw Extract (375mg), AP-Bio Andrographis Extract (250mg), Garlic (200mg), Sarsaparilla (75mg), and Berberine HCl (25mg).
Vital Plan was founded on Bill’s own story, where a physician becomes the patient. As shared on the official website, Bill underwent a period in his life where he was faced with debilitating pain and mysterious symptoms, none of which disappeared with conventional medicine. Being an avid researcher, he experimented with herbal therapies, which he grew fond of. Over the next ten years, he devoted time and energy to modern herbology, and just like that, he regained control over his health.
Ultimately, Bill and his daughter got together, “To empower people to take control of their health and provide easy access to his potent herbal blends.” Some facets that set this brand apart from others include their B Corporation certification (one that screams high standards of social and environmental performance, accountability, and transparency), ongoing educational resources, the existence of a health advisory board (physician oversight), third party testing, and reliance on science.Biome Boost
The second Vital Plan product to have qualified is Biome Boost, a premium tincture infused with five ancient herbs for advanced microbial support. As per the formulator, this broad-spectrum solution promotes health benefits that extend beyond the immune system to the other organs, tissues, and cardiovascular and respiratory systems. Two dropperfuls suffice to make a lasting impression as it encapsulates a 1920mg-proprietary blend of Cryptolepis, Houttuynia, Prickly Ash, Chinese Salvia, and Neem.Probiotic 40-Billion
Company: Vita Balance (Brand: VitaPost)Starting Price: $35
Probiotic 40-Billion is brought to us by VitaPost. Through this supplement, individuals will be supplying the body with immune-boosting, digestion-rectifying, and gut-balancing ingredients. Specifically, they include 40 billion CFU of L. acidophilus, L. Plantarum, B. lactis, and L. paracasei. The VitaPost brand is overseen by a leading natural health company, Vita Balance, serving the North American market.
With over 35 brands and counting, this team is “passionate about the benefits derived from natural health products.” Moreover, they are committed to “inspiring people to invest in their wellbeing.” Another company to rejoice over Mother Nature’s medicine, Vita Balance, pledges to “go to extreme measures to ensure that [they] source the finest ingredients from reputable suppliers” and to “carefully scrutinize international research studies.”DS-01
What initially attracted us to Seed is its minimalistic and sustainable design, but little does it suggest about its quality. Seed is a first-of-its-kind dietary supplement that includes clinically and scientifically studied probiotic strains for a healthy gastrointestinal system. Besides nurturing the GI system, DS-01 has the potential to induce healthy skin and heart, gut immune function, gut barrier integrity, and micronutrient synthesis.
What is it that makes DS-01 a first? It entails an accurate combination of 24 strains in B. longum, B. breve, L. Plantarum, L. rhamnosus, B. infantis, B. lactis, L. crispatus, L. casei, L. fermentum, L. reuteri, and B. adolescentis, and 400mgof Microbiota-Accessible Polyphenolic Precursors comprising of Pomegranate.
Concerning the possible reasons why one might choose Seed, rest assured there are plenty. In addition to the diversity among strains, ViaCap delivery technology was selected to promote survivability, third-party accredited laboratories tested over 400 allergens and pesticides, flow cytometry was used for precise enumeration of viable cells, and the supplement is heat, moisture, and light-protected (no refrigeration required).
That’s not all; their solution is based on research-derived potencies (53.6B AFU), provides systemic benefits beyond the gut, produces specific beneficial short-chain fatty acids, and is likely to support the expression of tight junction proteins in gut barrier cells. If these aren’t enough, DS-01 has been subjected to clinical studies! Our editorial team is completely in awe of Seed’s knowledge of probiotics, which they, fortunately, translated via their online resources. Ultimately, Seed is “a new standard in probiotics.”Ovuna
Ever considered probiotics as a solution for menopausal support? Ovuna is confident good bacteria can help relieve symptoms linked to menopause, may support healthy weight management, and aid overall gut health. How? The first strain, L. gasseri, is intended to maintain estrobolome (or bacteria in the gut that metabolizes estrogens) and good bacterial flora for vaginal health, B. breve was chosen for general health, and B. lactis to help absorb estrogens and boost immune function, which totals 15 billion CFU.
Other equally useful ingredients found per serving (2 capsules) include Chromium (400mg), Turmeric Extract (350mg), Moringa Powder (350mg), Curry Powder (150mg), Organic Sunflower Lecithin (200mg), and BioPerine (100mg). Our editorial team was astounded to see that Ovuna was originally priced at $89, which in our minds, was overpriced. Fortunately, the team brought it down to $49, a price we feel might resonate with most financial situations.
All Simple Promise products had to pass seven tests before being launched to the public. First, each ingredient met the “gold standard” of scientific evidence. Second, if there are double-blind human studies, the exact ingredient was incorporated. Then, we have clinical dosing, together with the second test. From there, all products had to be manufactured in cGMP-certified facilities. Third-party lab testing is next on their list of tests, as it identifies potential flaws. This step also includes pharmacology, toxicology, and other vital tests. Finally, the aforesaid six steps were reviewed and validated before proceeding.Complete Probiotics Platinum
We’ve finally arrived at the last probiotic solution, and it is none other than Complete Probiotics Platinum. The team at 1MD Nutrition maintains that this supplement has been designed to encourage the digestive tract’s normal microbial balance. This alone ensures gut and immune function. So, what’s in it, you ask? 51 billion CFU of L. acidophilus, B. lactis, B. longum, B. bifidum, L. plantarum, L. bulgaricus, L. casei, L. salivarius, LactoSpore, L. gasseri, and L. rhamnosus and NutraFlora Prebiotic (50mg). For safe travel to the intestines, the team resorted to delay-release capsules.
At 1MD Nutrition, the team’s mission is to help “people live longer, healthier lives through the powerful integration of advanced science and nature.” What actionable steps have been taken to ensure this? Each formulation represents the latest research news, nutrition, and fitness to make proper health decisions.
1MD Nutrition’s level of transparency is matchless, securing one of the top positions on our list. The team thoroughly explains everything, whether it be regarding the ingredient’s list or reasoning for a particular blend. Moreover, this brand is one of the fewest to launch a series of guides targeting different aspects of wellness. Clearly, the need for continued education depicts the team’s eagerness to contribute!Unearthing the Best Probiotic Supplements: Our Ranking System
Evidently, some brands took a similar approach to deal with gut health and symptoms linked to imbalances, while others thought outside of the box. Compared to our 2021 guide, this year’s selection (some of which were carried over). Credit goes to all parties involved in every formulation presented today. However, narrowing our opinions required extra support from our customizable ranking system. In short, this is a list of factors we felt were fundamental for a probiotics supplement to prevail. As long as most of the factors are checked off, we were open to choosing them. Here’s what our selection process was founded on:Manufacturing Reputation & Transparency
The first factor is anything and everything surrounding the manufacturer. It isn’t enough to know that such a company exists; individuals need to see whether answers to obvious questions are provided. Some examples of areas that must be clearly outlined include the selection process and sources of the ingredients, clear labeling, third-party testing, and other processes known to help convert raw material into a finished product. Even if a story is not told, it is the right of the consumer to know what goes into solutions. When a company fails to meet this basic requirement, nothing they do as the promotion will be memorable.Prebiotics & Other Angles of Attack
In most of the solutions listed above, the goal was to populate microbes further, but what about those already available? Nourishment is key, and this is where prebiotics enter the scene. These are fibers that are necessary for probiotics’ survival. Another possible angle of attack is fortifying the immune system. This is a common route because immune strength naturally implies fighting against invaders. A complete defeat is equivalent to a shield against the gut’s microbiome alteration. Companies that walk everyone through such angles were of utmost priority for our editorial team.Survivability Via Delivery
Continuing from above, probiotics are almost always effective when they reach the colon alive. What might influence strains’ survival rates? According to existing evidence, most probiotics don’t make it far because they are not resistant to our stomach acid. The only way to withstand the latter is to implement delivery technology. One example is MAKTrek 3-D, which has succeeded in preserving probiotics until the final destination.
Another example is ViaCap, a technology proven to keep probiotics viable through digestion regardless of the presence of stomach acid, bile salts, and digestive enzymes. Our editorial team generally wanted to see whether companies 1) factored in survivability and 2) discussed steps that guaranteed survivability.CFU Count
CFU, or “colony-forming unit,” measures viable bacterial or fungal cells. So, the more CFU there is in a supplement, the merrier, right? Not necessarily. On average, probiotic supplements offer 1 to 10 billion CFU writes one source [1], underlining that a product offering 40 billion or more doesn’t imply more healing. The need for a higher dose is usually determined based on one’s respective health, the severity of digestive problems, and the richness of their gut microbiomes.
In the probiotics industry, manufacturers are asked to list the total weight of microbes on their products’ supplement facts. The cellular mass reported includes both live and dead microorganisms. Therefore, high CFU counts neither suggest the number of viable units nor does it guarantee results faster. Also, remember that probiotics must be consumed before their shelf life. Otherwise, there’s no point in taking them. So, when we sought products, we were primarily curious to see whether manufacturers mentioned CFU counts at the end of the product’s shelf life.Proposed Use
Each probiotic strain has a unique intended use. Are we talking about weight loss? Bloating? Gut flourishment? Mood? The list is practically endless. Since certain strains have been studied to alleviate certain health conditions, our editorial team assessed whether the ingredient’s list matches the company’s aim for the product, along with the proper dosing.
For example, a company might promote L. rhamnosus for weight loss but fail to include the right dosage studied to work. In this case, one might either take more capsules than suggested (leading to a loss in value) or fail to see results. After researching the top studied strains, we verified the claims made. Anything that deviated from facts was disqualified.Education
Incorporating probiotics into one’s regimen is very complex because there are thousands of different strain combinations to consider. Any company that went the extra mile to expound upon their choices, to create a beginner’s guide on the different types and their influences, and decided to list research papers that support their decision was welcomed with open arms. Although we might have repeated this in numerous instances, it goes without saying that knowledge is mighty and can easily make or break one’s health.Storage
Storage requirements must be studied before use. Probiotics are generally sensitive to heat, water, and room temperature. Thus, the absence of care might only lead to a waste of money!
Based on our analysis, certain probiotics may not require refrigeration or special attention to moisture, but obviously, this doesn’t apply to all. Our goal was to ensure that each company provided clear instructions on storage. Otherwise, they were completely overlooked.Uniqueness
Uniqueness is open to interpretation, so we’ll let individuals decide for themselves how it should be defined. In the meantime, we see it as any characteristic that sets a product apart from another. Anything from a medical and/or scientific advisory board and clinically proven doses and ingredients to availability of supplement facts, lab testing, and their outcomes, money-back guarantees, and charitable efforts were reviewed and used for the process of elimination.Value for Price
Value for money is determined after the above-listed factors have been tallied per solution. The more substance a product houses, the more value it brings to one’s wallet and health. Many popular supplements prices soar through the roof with very little worth praising. We wouldn’t have realized this without a ranking system in place. Sadly, a lot of people blindly go with pricing alone. High or low, they can both deliver everything or nothing. Hence, individuals need to be watchful of what they see and read. The best way to tackle this is to question everything until there’s nothing left to ask. By the end, the product with all answers to pertinent questions succeeds!What are Probiotics?
Probiotics are made up of good live bacteria and/or yeasts that naturally reside within the body [2]. The fact that there are “good” versus “bad” types might be hard to wrap one’s head around, but they do exist. For instance, when individuals get an infection, the body has more bad than good, creating an imbalance in the environment. Good bacteria (in the form of probiotics) are recommended to help eliminate the extra bad lingering in the body. In doing so, a balance can be attained. To summarize, probiotic supplements either tend to exist good bacteria (reparation, maintenance, and flourishment), help populate good bacteria, or provide protection against foreign invaders by revamping the immune system.Gut Microbiome Fuels
Probiotics are just one piece of the gut, digestive, and overall health puzzle. Though they have been studied to elicit unique benefits, their survival and efficacy depend on other factors. Namely, these include:Prebiotics
Prebiotics are described as fuel for probiotics. Recall good bacteria are in place to help defeat excess bad bacteria. During this combat, the good that prevails isn’t always the case. In times of extreme damage, a healthy fuel source becomes fundamental. In this respect, we have prebiotics, which are trusted to feed the intestinal microbiota and deliver short-chain fatty acids to GI tracts and other distant organs [3].
As for the major types, they include subsets of carbohydrate groups. First, we have fructans, a group of prebiotics reckoned to stimulate lactic acid bacteria. Second, we have galacto-oligosaccharides (GOS), proven to stimulate Bifidobacteria and Lactobacilli genus. Starch and glucose-derived oligosaccharides are also beneficial, considering their positive influence on gut microbes. Others include pectic oligosaccharide (POS), arabinose, galactose, xylose sugars, ferulic acid, and cocoa-derived flavanols [3].Postbiotics
Once the body digests prebiotics and probiotics, the resulting waste products are called postbiotics [4]. Examples of postbiotics include vitamins B and K, amino acids, antimicrobial peptides (essential for slowing the growth rate of harmful bacteria), and short-chain fatty acids. One source that covered postbiotics inside and out referenced scientific evidence regarding its ability to promote positive change. These include lowered blood sugar levels, reduced risk of obesity and inflammation, assisting the immune and digestive systems, and uplifting probiotics function [5].Synbiotics
Finally, we have synbiotics, which refer to any supplement containing a blend of prebiotics and probiotics. In other words, individuals who resort to said supplements seek gut support, increase the number of beneficial bacteria, and ensure that the latter has the fuel to persist in achieving balance in their environment. The benefits include healthy digestion, immune and heart function, enhanced mental health, and decreased inflammation [6]. Luckily for all, there is plenty of diversity in the solutions offered!The Scientific Stance on the Top 3 Studied Probiotic Genus
Probiotics are identified by their specific strain, including the genus, the species, the subspecies (if applicable), and an alphanumeric strain designation explains one source [7]. The following brief will uncover scientific evidence on the top 3 genera of microbial organisms most often used in probiotic supplements. Precisely, we have:Lactobacillus
Lactobacillus is any genus of bacteria that can convert glucose into lactic acid as a by-product. This bacterium is popularly found in animal feeds, manure, silage, milk, and milk products. Described as having a rod-shaped body with a non-spore-forming feature, this friendly gram-positive bacterium is found in the human gut and oral cavity [8]. Popular among the strains is Lactobacillus acidophilus, which is predominantly located in the intestines.
Based on scientific evidence, the latter has been proven to help reduce cholesterol, may prevent and reduce the occurrence of diarrhea and vaginal infections, improve bowel-related symptoms, induce weight loss results, alleviate cold, flu, and allergy symptoms, lessen the effects of eczema, and support the gut. Speaking of gut health, L. acidophilus is reckoned to increase the amounts of Lactobacilli and Bifidobacterium and short-chain fatty acids [9].
The team at GundryMD [10] seems to be equally fond of L. reuteri because it is highly resistant to gastric acids and supports health and wellness through different actions. In particular, the team explained that taking L. reuteri might promote a healthy microbiome, immune function, cell health, healthy intestinal barrier, and digestive health. L. rhamnosus is yet another celebrated strain, as it is the most common type in our body.
Some of the benefits, as drawn by 1MD, include the ability to resist stomach acid, help protect against the environmental threat, has a great affinity for intestinal mucosal cells, or simply put, highly likely to colonize and thrive within the human gut, and many more [11]. It is important to note that these strains also come in different types, serving different purposes! Others worth reviewing include L. Plantarum, L. paracasei, L. gasseri, and L. casei.Bifidobacteria
Bifidobacteria species are found in the intestines and have been a go-to for treating diarrhea, constipation, and other intestinal disorders. This genus of bacteria is also liked for its ability to assist in the process of breaking down food, absorbing nutrients, and fighting invaders likely to cause diseases [12]. Another source referenced a board-certified pediatric neurologist, Dr. Sarah Rahal’s opinions on this genus. Specifically, she said, “Bifidobacterium confer a host of benefits to the health of the gut, brain, and metabolic and immune systems [13].”
The strains included are B. breve, B. longum, B. breve, and B. bifidum are usually delivered in probiotic supplements. One study evaluated the specific immune activation properties of the aforesaid four. The addition of a fifth called B. animalis lactis found that they all could “induce full dendritic cell maturation but showed differences in the levels of cytokine production.” In other words, different strains have different immune responses, which should be further explored [14].Bacillus
Bacillus is a genus of gram-positive, rod-shaped spore-forming bacteria with over 200 named species. Their spore-forming nature implies that the bacteria are heat stable and can survive acidic stomachs. Most importantly, spores are likely to germinate, grow and proliferate in the small intestine, ensuring a diverse microbiome [15].
That said, Dr. Alexander Rinehart, DC, CCN, CNS recommends spore probiotic formulations such as B. subtilis (produces antimicrobial compounds to control the growth of Helicobacter pylori), B. clausii, B. cereus, B. coagulans (essential for urinary tract infections), and B. licheniformis. Other noteworthy benefits include balanced immune function, production of key immune cells (macrophages, interferon, and natural killer cells), robust intestinal lining, improved response to allergy and infection, alleviated abdominal pain, bloating, and diarrhea linked to gut dysbiosis, and irritable bowel syndrome.
Besides the top trio, supplements have touted the benefits of the genus types: Saccharomyces and Streptococcus, poised to help treat various gastrointestinal disorders and strengthen the immune system, respectively.Possible Side Effects of Taking Probiotics
It should be clear that probiotics have a lot to offer, but this doesn’t necessarily mean individuals need not fear possible side effects. One-piece expounded on not one but five types that warrant further investigation, and they have been summarized as follows [16]:Unpleasant Digestive Discomfort
Have you ever heard the saying, “things will only get worse before they get better”? In some people, probiotics have demonstrated temporary digestive discomfort in gas and bloating. This is commonly experienced by those who resort to bacteria-based probiotics. If a solution contains yeast-based probiotics, the likely symptoms include constipation and increased thirst. Should any symptoms persist for more than a few weeks, individuals are asked to halt their consumption and to consult a medical expert immediately.Headaches
Probiotics are rich in a type of substance called biogenic amines, which supposedly form “when protein-containing foods age or are fermented by bacteria.” This particular substance has since been related to an exciting central nervous system, possibly leading to fluctuations in blood flow and thus, triggering headaches.Elevated Histamine Levels
Like amines, probiotics may also be rich in histamines. Normally produced in the immune system upon detecting a threat, when found in excess, histamines will dilate blood vessels to deliver more blood to the affected regions. At this point, vessels are more permeable and thus, allow immune cells to enter tissues to ward off pathogens. Individuals might experience redness and swelling and certain allergy symptoms during it all.Adverse Effects
Probiotic supplement facts must be carefully reviewed, as they may contain additional ingredients and/or sources of common allergens. People who have a recognized allergy and/or medical condition should review the label and consult a health professional before adding anything new to their respective regimens.Risk of Unwanted Infections
Unfortunately, for some people, taking probiotics has the reverse effect. In rare cases, bacteria or yeast might enter the bloodstream and cause infections. People at greatest risk include those who are immune-suppressed, have a history of prolonged hospitalizations, and those who underwent recent surgery. Once again, this is a rare phenomenon that individuals should merely be cautious of.Frequently Asked Questions About ProbioticsQ: What are probiotics?
A: Probiotics are good live bacteria that assist the digestive tract and immune system for whole-body wellness and utmost protection.Q: How do probiotics work?
A: They work in several ways. The first route is by populating the gut with more bacteria. The second route entails fueling existing probiotics in the gut and other pertinent body parts. The third route entails boosting the immune system to serve as a shield against bad bacteria.Q: Is the goal of probiotics to eliminate bad bacteria?
A: No, it turns out that the body requires some bad to remain in balance. In general, too much bad or good can be problematic. Probiotics only target any bad bacteria found in excess.Q: Who should consider taking probiotics?
A: Probiotics might be suitable for people suffering from diarrhea, inflammatory bowel disease, irritable bowel syndrome, yeast infections, skin conditions, weight fluctuations, stomach discomforts, and treating allergies and asthma, among others [17].Q: Are probiotics safe?
A: Yes, probiotics are generally safe to consume (under moderation); however, in rare cases, they might elicit unwanted side effects.Q: What is the best time to take probiotics?
A: Since probiotics require time to reach and populate the digestive tract, there supposedly is no best time of day to take them. Hence, we encourage everyone to follow the instructions provided on the supplement’s label.Q: What does proteolytic probiotic mean?
A: Also known as protease, a proteolytic probiotic has the ability to digest proteins (long chain-like molecules of protein) into peptides and amino acids [18].Q: What is the difference between “probiotic” and “spore probiotic”?
A: The difference rests in the genus. The only genus that offers spore probiotics is Bacillus. The latter is usually considered to ensure the survivability of bacteria in extreme outer environments.Q: What is rhamnosus, a genus or a strain?
A: When you see the probiotic strain “Lactobacillus rhamnosus” or “L. rhamnosus,” the first word identifies the genus, whereas the second word identifies the species. Certain strains also have subspecies, such as B. animalis lactis, where “lactis” serves as the subspecies.Q: Where specifically in the body do probiotics live?
A: Oftentimes, probiotics are situated in the gut, mouth, vagina, urinary tract, skin, and lungs [2].Q: What is the microbiome?
A: The human body is composed of microbes. The total of all microbes is what we refer to as the microbiome. In fact, we inherit microbes from our mothers. Given that there are 40,000 possible species, there’s an infinite number of combinations, which makes each human unique from one another.Q: What is the difference between microbe, microbiota, and microbiome?
A: Microbe is a generic term used to describe all living microorganisms (bacteria, fungi, viruses, etc.). Microbiota is a community or collection of microbes. Finally, the microbiome is an entire ecosystem of microbiota. Each human’s microbiome/ecosystem is unique and provides insight into their biological information.Q: What do CFU and AFU mean?
A: CFU stands for colony-forming units, whereas AFU stands for active fluorescent units. CFU indicates how many “living and active” bacterial cells are delivered per serving. It is important to assess whether the indicated CFU is “at the time of manufacture” or “at expiry.”
If it is the former case, CFU counts might not reflect the product’s worth because they reduce in number with time. On the other hand, AFU represents a count of “living and viable” bacteria in a probiotic. The two measurements are retrieved differently but arrive at the same conclusion [19].Q: How is CFU measured?
A: CFU is measured by plating on an agar plate [19].Q: Why is MAKTrek 3-D important?
A: MAKTrek 3-D is a three-step system scientifically demonstrated to keep many probiotic bacteria alive compared to other delivery systems.Q: What are natural sources of probiotics?
A: Top food sources for probiotics include tempeh, miso, yogurt, kefir, buttermilk, cheese, kimchi, sauerkraut, pickles, and kombucha, say the least.Q: What are natural sources of prebiotics?
A: Some examples of food sources that carry an apt source of prebiotics include chicory root, dandelion greens, artichokes, garlic, onions, leeks, asparagus, bananas, barley, oats, apples, konjac root, cocoa, burdock root, flaxseeds, yacon root, jicama root, wheat bran, and seaweed [20].Q: Will probiotic supplements help with weight management?
A: Probiotic supplements have the potential to aid with weight management, but they are unlikely to promote drastic changes. The idea is that by diversifying the gut microbiome, other areas of health will improve, ensuring balance all around. This also means properly functioning metabolism for healthy bowel movements and weight loss. Obviously, the best results come to those who follow a healthy diet and exercise routine.Q: What are the best probiotic supplements of 2022?
A: Refer to our top picks right above. Most of them have a lot to offer in terms of the gut and immune support, while a select few may warrant further investigation.The Top 33 Best Probiotic Supplements in 2022 Final Verdict
The human body is made up of trillions of bacteria. Hence, it is sensical for probiotics to exist. People tend to find comfort in probiotics because of their ability to populate the gut and promote balance, two facets critical for wellness. In searching for top performers, our editorial team landed on 33 of the best probiotic solutions. Although some took similar approaches, others took our breath away. The latter types of companies are transparent from beginning to end, educate consumers on what they will be consuming and the influence over time, and list scientific backing for soundness.
Our intention for this guide is to go beyond listing the best of the best. The key takeaway here is that everything must be thoroughly researched before ordering. Given the rise of scam products, individuals must be willing to question everything for their health. Those left standing with thorough answers is worth investing in. Until we see the need to update our top probiotics supplement again, we hope we succeeded in shedding light on the significance of probiotics. Remember, our analysis is just the beginning; there’s so much more unraveling!
ALSO READ:Compare the Top 22 Best Weight Loss Supplements to Buy in 2022
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Please understand that any advice or guidelines revealed here are not even remotely substitutes for sound medical or financial advice from a licensed healthcare provider or certified financial advisor. Make sure to consult with a professional physician or financial consultant before making any purchasing decision if you use medications or have concerns following the review details shared above. Individual results may vary as the statements regarding these products have not been evaluated by the Food and Drug Administration or Health Canada. The efficacy of these products has not been confirmed by FDA, or Health Canada approved research. These products are not intended to diagnose, treat, cure or prevent any disease or provide any kind of get-rich money scheme.
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